"Understanding the Molecular Basis of Cardiac and Skeletal Muscle Disease"
Prof. Dr. Ju Chen
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Ju Chen, PhD.
Professor of Medicine
AHA Endowed Chair
Director of Basic Cardiac Research
School of Medicine
UC San Diego
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About the Lab
My lab is interested in understanding the molecular basis of cardiac and skeletal myopathy. We are also studying a number of signaling pathways underlying cardiac hypertrophy and heart failure.
More about our research >
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Spotlight on:
- October 2018: IP3R1 plays a critical role in regulating physiological function of the GI tract – a new manuscript in the Journal of Gastroenterology. More information here.
- October 2018: Ubqln is significant in cardiac ubiquitination-proteasome coupling – a new manuscript in ‘JCI’. More information here.
- August 2018: Generation and analysis of striated muscle selective LINC complex protein mutant mice – a new manuscript in Methods Molecular Biology. More information here.
- August 2018: Cell surface marker signatures are a broadly applicable strategy for the enrichment of ventricular cardiomyocytes derived from human embryonic stem cells - a new manuscript in Stem Cell Reports. More information here.
- August 2018: TBX20 plays a key role in atrial development - a new manuscript in Circulation Research. More information here.
- May 2018: The deficiency of PRKD2 triggers hyperinsulinemia and metabolic disorders – a new manuscript in Nature Communications. More information here.
- April 2018: aPKCζ-dependent repression of Yap is necessary for functional restoration of irradiated salivary glands with IGF – a new manuscript in Scientific Reports. More information here.
- March 2018: Luma is not essential for murine cardiac development and function – a new manuscript in Cardiovascular Research. More information here.
- February 2018: Infarct fibroblasts do not derive from bone marrow lineages – a new manuscript in Circle Research. More information here. Older news.
