Ju Chen Laboratory In the Department of Medicine

"Understanding the Molecular Basis of Cardiac and Skeletal Muscle Disease"

Prof. Dr. Ju Chen

  • Ju Chen, PhD.
    Distinguished Professor of Medicine
    AHA Endowed Chair
    Co-Director, Molecular Cardiology Program
    UCSD School of Medicine

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About the Lab

My lab primarily focuses on understanding the molecular basis of cardiac and skeletal myopathies and heart failure, with a concurrent effort to develop potential therapies for these conditions.
More about our research >

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Spotlight on:

  • December 2025: ASNA1 is essential for cardiac development and function by regulating tail-anchored protein stability and vesicular transport in cardiomyocytes. More information here.
  • December 2025: DNA Damage and repair in Cardiomyopathy: Mechanisms and Therapeutic Opportunities. More information here.
  • November 2025: ALPK3 Cardiomyopathy: Integrative Review With Systematic Variant Curation, Mechanisms, and Translation. More information here.
  • November 2025: A Novel miniALPK3 Gene Therapy for ALPK3-Associated Cardiomyopathy. More information here.
  • Older news here.

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