"Understanding the Molecular Basis of Cardiac and Skeletal Muscle Disease"
Prof. Dr. Ju Chen
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Ju Chen, PhD.
Professor of Medicine
AHA Endowed Chair
Director of Basic Cardiac Research
School of Medicine
UC San Diego
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About the Lab
My lab is interested in understanding the molecular basis of cardiac and skeletal myopathy. We are also studying a number of signaling pathways underlying cardiac hypertrophy and heart failure.
More about our research >
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Spotlight on:
- March 2019: RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure. More information here.
- March 2019: Kindlin-2 Is Essential for Preserving Integrity of the Developing Heart and Preventing Ventricular Rupture. More information here.
- February 2019: The BAG3 dependent and independent roles of cardiac small heat shock proteins - a new article in JCI Insight. More information here.
- February 2019: Inositol 1,4,5-Trisphosphate Receptors in Endothelial Cells Play an Essential Role in Vasodilation and Blood Pressure. More information here.
- February 2019: Combinatorial interactions of genetic variants in human cardiomyopathy. More information here.
- February 2019: P209L mutation in Bag3 does not cause cardiomyopathy in mice. More information here.
- December 2018: A secretory pathway kinase regulates sarcoplasmic reticulum Ca2+ homeostasis and protects against heart failure. More information here. Older news here.
