Ju Chen Laboratory In the Department of Medicine

"Understanding the Molecular Basis of Cardiac and Skeletal Muscle Disease"

Prof. Dr. Ju Chen

  • Ju Chen, PhD.
    Professor of Medicine
    AHA Endowed Chair
    Director of Basic Cardiac Research
    School of Medicine
    UC San Diego
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About the Lab

My lab is interested in understanding the molecular basis of cardiac and skeletal myopathy. We are also studying a number of signaling pathways underlying cardiac hypertrophy and heart failure.
More about our research >

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Spotlight on:

  • September 2021: Loss of Eukaryotic Elongation Factor 1 A2 in Murine Myocardium Results in Dilated Cardiomyopathy. More information here.
  • August 2021: PTPMT1 Is Required for Embryonic Cardiac Cardiolipin Biosynthesis to Regulate Mitochondrial Morphogenesis and Heart Development. More information here.
  • August 2021: Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere. More information here.
  • April 2021: mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif. More information here.
  • April 2021: Molecular Characterisation of Titin N2A and Its Binding of CARP Reveals a Titin/Actin Cross-linking Mechanism. More information here.
  • Older news here.

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