Ju Chen Laboratory In the Department of Medicine

"Understanding the Molecular Basis of Cardiac and Skeletal Muscle Disease"

Prof. Dr. Ju Chen

  • Ju Chen, PhD.
    Professor of Medicine
    AHA Endowed Chair
    Director of Basic Cardiac Research
    School of Medicine
    UC San Diego
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About the Lab

My lab is interested in understanding the molecular basis of cardiac and skeletal myopathy. We are also studying a number of signaling pathways underlying cardiac hypertrophy and heart failure.
More about our research >

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Spotlight on:

  • April 2019: Nexilin is a New Component of Junctional Membrane Complexes Required for Cardiac T-Tubule Formation. More information here.
  • March 2019: RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure. More information here.
  • March 2019: Kindlin-2 Is Essential for Preserving Integrity of the Developing Heart and Preventing Ventricular Rupture. More information here.
  • February 2019: The BAG3 dependent and independent roles of cardiac small heat shock proteins - a new article in JCI Insight. More information here.
  • February 2019: Inositol 1,4,5-Trisphosphate Receptors in Endothelial Cells Play an Essential Role in Vasodilation and Blood Pressure. More information here.
  • February 2019: Combinatorial interactions of genetic variants in human cardiomyopathy. More information here.
  • February 2019: P209L mutation in Bag3 does not cause cardiomyopathy in mice. More information here.
  • Older news here.

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