Ju Chen Laboratory In the Department of Medicine

"Understanding the Molecular Basis of Cardiac and Skeletal Muscle Disease"

Prof. Dr. Ju Chen

  • Ju Chen, PhD.
    Distinguished Professor of Medicine
    AHA Endowed Chair
    Co-Director, Molecular Cardiology Program
    UCSD School of Medicine

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About the Lab

My lab primarily focuses on understanding the molecular basis of cardiac and skeletal myopathies and heart failure, with a concurrent effort to develop potential therapies for these conditions.
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Spotlight on:

  • January 2025: Illuminating understudied kinases: a generalizable biosensor development method applied to protein kinase N. More information here.
  • December 2024: Inositol 1,4,5-Trisphosphate Receptor 1 Gain-of-Function Increases the Risk for Cardiac Arrhythmias in Mice and Humans. More information here.
  • November 2024: RBPMS and RBPMS2 Cooperate to Safeguard Cardiac Splicing. More information here.
  • May 2024: A therapeutic leap: how myosin inhibitors moved from cardiac interventions to skeletal muscle myopathy solutions. More information here.
  • Older news here.

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